Smith+Nephew’s VISIONAIRE™ Patient-Specific Instrumentation shown to improve outcome measures for total knee arthroplasty compared with conventional instrumentation

March 6, 2023

Smith+Nephew (LSE:SN, NYSE:SNN), the global medical technology company, today announces a systemic literature review and meta-analysis1 of its VISIONAIRE Patient-Specific Instrumentation (PSI) showing that its use leads to improvements in alignment accuracy, efficiency in surgical procedures, and reduction in length of hospital stay in comparison with conventional instrumentation.1

The research was published online by the Archives of Orthopaedic and Trauma Surgery. Twenty-five (25) relevant studies were included in the meta-analysis, all of which compared VISIONAIRE PSI-enabled Total Knee Arthroplasty (TKA) with conventional instrumentation-enabled TKA. Each study reported on one or more of the following outcome measures: alignment accuracy, intraoperative outcomes (indicative of efficiency), and postoperative outcomes.

The studies demonstrate that, compared to TKA carried out with conventional instrumentation, patients who received VISIONAIRE PSI-enabled TKA experienced the following statistically significant results:

  • A 40% reduction in the odds of an outlier in the mechanical axis.
  • More efficient operations, with reductions in operating room time, turnover time, and tourniquet time.
  • A 53% reduction in the odds of requiring a blood transfusion.
  • An 11.1% reduction in mean length of hospital stay.

Accurate alignment (+/-3 degrees from neutral) has been shown to correlate with long term arthroplasty survivorship.2-4 This meta-analysis provides evidence of reduced odds of mechanical axis outliers versus conventional instrumentation.

“Utilizing Smith+Nephew’s VISIONAIRE preoperative planning and intraoperative cutting guides has allowed me to be more accurate, less invasive, and more efficient with both inpatient and outpatient total knee replacements,” commented Dr. Ravi Bashyal, Orthopedic Surgeon and Director of Outpatient Hip and Knee Replacement Surgery at NorthShore University HealthSystem. “This has resulted in improved outcomes, streamlined tray utilization, and ultimately a happier, more satisfied surgeon and patients. It’s even been shown in a retrospective study that total hospital costs were statistically significantly lower for TKA with VISIONAIRE than TKA without PSI.5

Smith+Nephew’s VISIONAIRE Patient-Specific Instrumentation includes customized cutting guides designed to reduce the number of steps and surgical instruments required for surgery compared to conventional TKA, creating a simplified surgical environment,1,6 with virtually no in-hospital incremental costs for payors, with post-acute cost savings due to a reduction in the likelihood of readmissions.5 The guides are designed from surgeon-specific preferences, then developed by a dedicated engineer, allowing for personalised performance.

To learn more about Smith+Nephew’s VISIONAIRE Patient-Specific Instrumentation, please visit

About Smith+Nephew

Smith+Nephew is a portfolio medical technology company focused on the repair, regeneration and replacement of soft and hard tissue. We exist to restore people’s bodies and their self-belief by using technology to take the limits off living. We call this purpose ‘Life Unlimited’. Our 19,000 employees deliver this mission every day, making a difference to patients’ lives through the excellence of our product portfolio, and the invention and application of new technologies across our three global franchises of Orthopaedics, Sports Medicine & ENT and Advanced Wound Management.

Founded in Hull, UK, in 1856, we now operate in more than 100 countries, and generated annual sales of $5.2 billion in 2022. Smith+Nephew is a constituent of the FTSE100 (LSE:SN, NYSE:SNN). The terms ‘Group’ and ‘Smith+Nephew’ are used to refer to Smith & Nephew plc and its consolidated subsidiaries, unless the context requires otherwise.

For more information about Smith+Nephew, please visit

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